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OCTN2 ( SLC22A5 ) is not only a Na + -independent organic cation transporter but also a Na + -dependent and high-affinity carnitine transporter, which is widely distributed in various tissues such as kidney, intestine, placenta, breast, liver, heart, testis, skeletal muscle and bloodbrain barrier [161]
Dysregulation of ERAD can lead to an accumulation of misfolded proteins in cardiomyocytes, contributing to the pathogenesis of heart disease
Studies suggest 2,000 mg daily provides optimal benefits
Etrusco, A., Lagan, A
PLOS ONE, 15(9), e0239252
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