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The interactions of these substituents, both polar and nonpolar, often causes the protein to fold into spherical conformations which gives this class its name
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When this occurs, it can include numerous symptoms and sometimes blurred vision
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By week 3 at any given dose, most people feel normal again
Borrell-Pags M, Canals JM, Cordelires FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, et al
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