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In addition, although both receptors facilitate chemoresistance to the selective estrogen receptor modulator (SERM) tamoxifen in breast cancer, resistance to tamoxifen is characterized by decreased expression of IGF-1R and increased EGFR expression, and more surprisingly, no detectable difference was found in EGFR expression between breast cancer cells resistant and sensitive to tamoxifen when measured with cytometry (79)
Because we could observe significant numbers of Ki-67+ matrix keratinocytes even in NTAPP-untreated hair bulbs, the effect of NTAPP might be obscured in ex vivo conditions in which exogenous factors stimulating hair growth may exist
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[4] Hagen TM et al
References Torre E, Vetrano S, Vertu S, Zazzaron M, Russo R
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