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Preclinical and clinical studies demonstrate BBRs multimodal anti-obesity mechanisms: (i) adenosine monophosphate-activated protein kinase (AMPK) activation enhancing lipolysis and -oxidation, (ii) peroxisome proliferator-activated receptor (PPAR-) suppression inhibiting adipogenesis, (iii) gut microbiota modulation improving metabolic endotoxemia, and (iv) uncoupling protein 1 (UCP1) upregulation promoting adipose browning
PMID 12908852
Furthermore, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of DEPs mainly included nucleotide excision repair and p53 signaling pathway (Fig
Comparison of essential amino acids vs dietary protein and protein supplements for building muscle
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