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Recently, they have exposed exciting insights into tumorigenesis
Deciphering the molecular determinants of VCs context-dependent anticancer effects may accelerate its rational clinical deployment
Many methodological validations were not included because of the limited space of the article
The omega-3 fatty acids docosahexaenoic acid and eicosapentaenoic acid serve a role in reducing the resistance of tumor cells to bortezomib by activating the serine synthesis pathway, mitochondrial folate cycle, methionine cycle-associated GSH synthesis and ChaC1-mediated GSH degradation in tumor cells, ultimately promoting GSH degradation (138)
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