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DOI: 10.1038/s41389-017-0025-3 55
Lyons J, Rauh-Pfeiffer A, Ming-Yu Y, Lu XM, Zurakowski D, Curley M, et al
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AOP Development Strategy Context Used to provide background information for AOP reviewers and users that is considered helpful in understanding the biology underlying the AOP and the motivation for its development.The background should NOT provide an overview of the AOP, its KEs or KERs, which are captured in more detail below
Off-label use is carried out solely at the doctor's clinical discretion and responsibility, with the patient's fully informed consent
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