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Tight junctions produce high transendothelial cell electrical resistance, impeding ions and small charged molecules from crossing the BBB (Blanchette and Daneman, 2015)
Independently tested - purity printed on the lab report
at the 3 IU per mg convention these map to the International Unit values below
Moreover, the chemical nature of the C-terminal residue side chain determines ligand contact with RAMP and can influence activity at AMYRs and CTR 18,19
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