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10.1161/ATVBAHA.120.314515 Arterioscler Thromb Vasc Biol

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Single cell deconvolution was conducted by employing the nonparametric Wilcoxon test to calculate the P-value for each dataset and then applied additive method for combining the p-values from the independent datasets

A subsequent pilot study (n=12) comparing oral liposomal glutathione (500 mg twice daily for 2 weeks) found increases in GSH levels in whole blood, erythrocytes, and plasma, along with reductions in 8-isoprostane (a marker of oxidative stress) (Buonocore et al., Oxid Med Cell Longev, 2016) [16]