Call 911 or seek emergency medical attention immediately if you experience: Severe or persistent dizziness that prevents normal activities Lightheadedness accompanied by chest pain, shortness of breath, or irregular heartbeat Fainting or loss of consciousness Dizziness with severe headache, vision changes, or difficulty speaking Signs of severe dehydration (dark urine, extreme thirst, confusion, minimal urination) Severe abdominal pain, especially if radiating to the back (possible pancreatitis) Severe pain in the upper right abdomen, fever, or yellowing of skin/eyes (possible gallbladder disease) Contact your doctor within 24-48 hours if you experience: Recurrent lightheadedness that occurs multiple times daily Dizziness that worsens over time rather than improving Lightheadedness accompanied by persistent nausea, vomiting, or diarrhea Symptoms that interfere with daily activities or quality of life New onset of dizziness after a dose increase Symptoms of hypoglycemia that do not improve with carbohydrate intake Before your appointment, document when the lightheadedness occurs (timing relative to medication administration, meals, or position changes), its severity and duration, and any accompanying symptoms

Several case reports have documented pregnancies in women using semaglutide for weight loss, suggesting that improved metabolic health may restore ovulatory function rather than impair it
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As expected for the class, the most frequent adverse events were gastrointestinal effects, which were mostly mild-to-moderate in severity and transient