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Hepatoprotective activity of picroliv, curcumin and ellagic acid compared to silymarin on paracetamol induced liver toxicity in mice

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Consistent with cell-autonomous effects, the epigenetic control of OPC differentiation into myelinating OLGs is disrupted with aging (Shen et al., 2008), and the OPCs of aged mice fail to respond to growth factors and differentiation signals (Neumann et al., 2019)