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While several editorials have expressed concern regarding the disproportionate reporting of retinal adverse events associated with GLP-1 RA use in specific studies, there remain a number of broad limitations

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Potential benefits: Initial trials of semaglutide showed that the drug not only could effectively control type 2 diabetes, but also led to an average weight loss of 8 to 10 pounds

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While GLP-1 receptor agonists (such as semaglutide and liraglutide) have demonstrated significant benefits in diabetes management, weight reduction, and cardiovascular outcomes in clinical trials, enhancing physiological GLP-1 through dietary and lifestyle modifications represents a foundational approach