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The distinctive characteristics of cells undergoing ferroptosis include a series of morphological abnormalities of mitochondria, such as organelle shrinkage, condensed organelle membrane, and lessened cristae

Temperature fluctuations, freeze-thaw cycles, shaking, and high concentrations all promote aggregation

demonstrated that in dendritic cells (DCs), LPS-induced glycolysis is repurposed to replenish citrate, an intermediate metabolite in the TCA cycle that is depleted for the de novo synthesis of fatty acids ( 2 ( de novo lipogenesis is important for phagocytosis as it requires ongoing lipid synthesis in the ER for membrane expansion, such that Ms can surround and capture targeted pathogens for internalization ( de novo lipogenesis, an anabolic process that is NADPH-dependent, in regulating the inflammatory response of myeloid cells

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Presented for research literature review only Covarrubias AJ et al