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The glucagon receptor activation in both compounds may partially mitigate this through increased protein turnover and metabolic activation, but the extent of muscle preservation has not been specifically studied in dedicated body composition analyses for either compound

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Here, we present the example of the SCALE phase 3a program, investigating the efficacy and safety of liraglutide 3.0 mg for weight management, to demonstrate this, as different methods of analysis were required by the EMA compared with the FDA (Table 2)

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Published online 2017 Sep 22