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Buse, M.D., from the University of North Carolina School of Medicine in Chapel Hill, and colleagues randomly assigned 2,713 adults with inadequately controlled type 2 diabetes receiving metformin with or without SGLT2i with overweight or obesity to receive cagrilintide-semaglutide, semaglutide, cagrilintide, or placebo for 68 weeks

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Tirzepatide is the active ingredient in Mounjaro and Zepbound, both authorized by Health Canada

Consequently, the present review aims to more comprehensively summarize the current understanding of the involvement of GLP-1RAs across distinct categories of pain, elucidate their mechanisms of action, and shed light on the future direction of clinical investigations by incorporating findings from newly published studies on GLP-1RAs in pain modalities

Effects of noise exposure on development of tinnitus and hyperacusis: Prevalence rates 12 months after exposure in middle-aged rats