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In abdominal aorta anastomosis models, the peptide prevents and reverses thrombus formation, suggesting antithrombotic effects mediated through endothelial protection and normalized coagulation cascade activity

But emerging evidence suggests GLP-1 and GLP-1/GIP therapy may be associated with changes in thyroid function tests in some patients

doi: 10.1016/S0140-6736(21)00213-0 21 WildingJPHBatterhamRLCalannaSDaviesMVan GaalLFLingvayIet al

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If these signals are already paradoxical while the patient is awake, it compromises the ability to accurately assess apnea types later