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Setup can quickly become a bottleneck when global logistics, assessment builds, and site readiness all need to align

Thus, melatonin appears to be a good candidate for neuroprotection because of its safety profile and different protective effects, including ROS scavenging, excitotoxic cascade blockade, and modulation of neuroinflammatory pathways 140

Month-over-month ADM prescribing increased from December 2024 to January 2025, then remained relatively stable until March 2025

It is often used to help stabilize energy and appetite throughout the day

The statistical significance of the difference between two means assessed twice for the same research group was evaluated using a paired t-test or and Wilcoxon signed-rank test