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Unlike compounds that act directly on peripheral vascular pathways, PT-141 has been studied for central nervous systemmediated melanocortin activity
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However, UV exposure carries well-documented risks , including premature aging , sunburn , hyperpigmentation , and increased risk of skin cancer , especially in fair-skinned individuals
Yoon S, Seger R (2006) The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions
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