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Discovering new clinical approaches for existing and approved drugs provides opportunities to extend the lifespan and market potential of the existing drugs, as shown for GLP-1RAs and other pleiotropic drugs

Patients with T2DM experience a significant decline in the incretins functional properties which causes delayed and reduced insulin release after glucose administration and impairs glucose tolerance [12,13,14]

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Regulation of cardiac energy metabolism in newborn

It is possible that their pharmacokinetic profiles will be enhanced relative to tablet formulation in patients with gastroparesis