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If more than 3 days have passed since the last dose, reinitiate Xultophy at the recommended starting dose to mitigate GI side effects
If other items in the back are also freezing, turn the temperature up slightly
CSU cannot be regarded as a typical Th2 disease but there are a subgroup of patients with Th2-related comorbidities and increased levels of circulating Th2 cytokines
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Gastrointestinal symptoms including nausea, vomiting, diarrhea, constipation, and abdominal discomfortare the most frequently reported adverse effects, occurring in 20-30% of patients (varying by dose and population), particularly during dose escalation
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