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The broader 2026 context matters: as of May 2026, the FDA has proposed regulatory changes affecting compounded semaglutide and tirzepatide, with a public comment period closing June 29, 2026
is currently unavailable due to new government restrictions
The approval is supported by the OASIS clinical trial programme, where participants achieved around 17% average weight loss, with nearly one in three losing 20% or more, alongside lifestyle intervention
Eur J Immunol 46(1):223229
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