What they found: Mean weight loss: 2.6 kg vs 2.3 kg placebo , a difference of only 0.3 kg (1 %) Statistically non-significant Clinically unsatisfactory for the obesity indication Safety profile remained favorable Why it matters: The study stopped the development of AOD-9604 as a drug
Therefore , all research involving BPC-157 peptide remains limited to in vitro and preclinical laboratory research models
The brand's FAQ states that BPC-157 is "considered safe when used as directed" based on preclinical trial data showing no significant side effects at recommended dosages - that is the company's characterization, attributed here as such
Glutathione S-transferases [PMID: 2199257] Laboratory literature summary: Glutathione S-transferases
By inhibiting NNMT, it can increase intracellular NAD+ levels, activate longevity proteins SIRT1/SIRT3, enhance mitochondrial function and fat metabolism, and is widely used in metabolic regulation, obesity, insulin resistance and aging-related scientific research experiments