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The clinical consequence ranges from local inflammation through to systemic hypersensitivity and antibody formation

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3A,B, after 2 h of co-incubation, the uptake rates of DiI, DiI@Lip and DiI@Tf-Lip were 17.4, 28.7 and 36.5%, after 4 h of co-incubation, the uptake rates of DiI, DiI@Lip and DiI@Tf-Lip were 32.1, 47.7 and 67.7%, after 8 h of co-incubation, the uptake rates of DiI, DiI@Lip and DiI@Tf-Lip were 44.6, 72.8 and 85.1%

Briefly, the treated cells were seeded at a precise density for overnight culture, washed with basic medium, and equilibrated at 37 C for 1 h