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Presented for research literature review only Shiratori Y et al

AMPK phosphorylates NAMPT to regulate NAD(+) homeostasis under ionizing radiation [PMID: 36196536] Laboratory literature summary: AMPK phosphorylates NAMPT to regulate NAD(+) homeostasis under ionizing radiation

Liu Y, Niu R, Deng R, Song S, Wang Y, Zhang H

Importantly, the association was more pronounced in patients with obesity/overweight, indicating a potential protective effect against CRC that may be partly driven by weight loss, as well as other mechanisms unrelated to weight loss

[13] [16] These gastrointestinal effects are dose-dependent and mostly mild-to-moderate in severity