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Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Substudy: Loomba R, Hartman ML, Lawitz EJ, et al

At steady state, the exposure (in terms of AUC 0168 h,SS , C avg and C max,SS ) of semaglutide 1.0 mg appeared to be approximately double that of semaglutide 0.5 mg, while clearance and distribution appeared similar for both doses

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However, it is not known whether this specific enzyme defect was responsible for the patients chronic hemolytic anemia

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