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They have come into the limelight after a large double-blinded study published in NEJM, showed an average 14.9% decrease in weight in obese patients given semaglutide on top of lifestyle modifications, compared to 2.4% in the control arm (see research summary at end)
Vanlandewijck M, He L, Mae MA, et al
L-carnitine improves cardiovascular health by reducing oxidative stress and inflammation, beneficial for heart disease patients
& Mecsas, J
The SELECT trial demonstrated semaglutide reduces major adverse cardiovascular events by 20% in non-diabetic patients, repositioning GLP-1 drugs as disease-modifying therapies
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