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Potential Role in Managing Chronic Illnesses Research suggests that glutathione may play a supportive role in managing conditions like diabetes, Parkinsons disease and autoimmune disorders due to its antioxidant and detoxifying properties

After exposure to electrophilic or oxidative stress, the sensor residues cysteine of Keap1, especially C151, C226, C273, and C288, undergo oxidation and modification, causing conformational changes that inhibit Keap1-mediated NRF2 degradation [94]

Verghese, J., Abrams, J., Wang, Y