The plates were read on a BMG LabTech ClarioStar Plus plate reader using BMG ClarioStar MARS software (version 4.20) to detect luminescence as a readout for cell viability (% relative to DMSO)
Disclaimer: This statement has not been evaluated by the U.S
Differential interactions of ethacrynic acid and diethyl maleate with glutathione [PMID: 39477623] Laboratory literature summary: Differential interactions of ethacrynic acid and diethyl maleate with glutathione S-transferases and their glutathione co-factor in the
In simple terms, 5-Amino-1MQ works by blocking an enzyme called NNMT (nicotinamide N-methyltransferase)
Oxygen tension, serum supplements, inflammatory priming, passage number, and culture format can alter MSC respiration, senescence, EV output, and secretome composition [19,20,21,22,23,24]