Proton pump inhibitors and similar medications that lower stomach acid might decrease the absorption of vitamin B12 from food, but this is less of a concern when receiving B12 injections because they bypass the digestive system entirely
note that daily dosing is only for the activation phase of the GLOW protocol (weeks 1-4) , decreasing to 5x per week for the remodeling phase (weeks 5-8), and further reduced to 2-3x per week during maintenance (weeks 9-12)
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Treatment involves addressing the cause and sometimes vitamin B12 supplements or injections
Forms of Vitamin B12 and Who They Suit B12 Form How Its Taken Best For Tablets/Capsules Swallowed with water Mild deficiency, general wellness, everyday convenience Sublingual tablets Dissolve under the tongue People who may not absorb well through the gut Nasal spray Sprayed into the nostril Those who dislike pills or injections Injections Given in clinic or at home (prescribed) Confirmed deficiency, absorption issues, and faster results Oral tablets and capsules are convenient, but they must pass through the digestive system, which can limit absorption in people with gut issues, low stomach acid, or certain surgeries