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IGF-1 LR3 (Long R3 IGF-1) is a synthetic analog constructed by adding a 13-amino-acid N-terminal extension and substituting arginine for glutamic acid at position 3 of the mature IGF-1 sequence
Brand, 2010
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Under these circumstances a thiyl radical is formed that will initiate and propagate an oxygen-dependent chain reaction, involving peroxyl radical formation that will lead to further consumption of intracellular GSH (Quijano et al., 1997)
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