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Thymidylate synthase reduces 5,10-methylene THF back to dihydrofolate (DHF) and converts dUMP (deoxyuridine monophosphate) into dTMP (deoxythymidine monophosphate or thymidylate), which is a precursor for nucleic acid synthesis
When to Consider Vitamin B12 Injections If You Have a Deficiency : People who have been diagnosed with a vitamin B12 deficiency, especially those with underlying health conditions that affect absorption, may benefit from the rapid absorption and higher bioavailability offered by injections
Lefevre M, Redman LM, Heilbronn LK, et al
Pregnant and breastfeeding individuals, those on anticoagulants or with bleeding disorders, and anyone with documented B12 toxicity (extremely rare) require provider consultation
The EC50 in the above example is 1.3 nM (11.7 ng/mL)
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