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The decrease in the level of expression of genes responsible for the synthesis of superoxide dismutase increases with the increase in glutamine concentration

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The dry and wet forms of beriberi involve peripheral neuropathy, whereas cerebral beriberi can lead to neuronal cell death and the clinical conditions of Wernicke's encephalopathy and Korsakoff's psychosis, especially in those who chronically abuse alcohol (22, 24)

It is not strictly unexplored, nor is it a failed target