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Mao C, Wang X, Liu Y, Wang M, Yan B, Jiang Y, et al
Consumers may think theyre getting a blockbuster GLP-1 drug like semaglutide the active ingredient in Ozempic and Wegovy or tirzepatide the active ingredient in Mounjaro and Zepbound in a format thats applied to the skin
A large real-world study shows that patients who stop popular GLP-1based weight-loss drugs often return to treatment or try alternative therapies, helping explain why average weight regain after discontinuation may be smaller than expected
The mechanistic background lies in the triple receptor activation
Its ability to cross the blood-brain barrier means it plays an important role in removing toxins from the brain and other cells
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