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Pharmacokinetics and pharmacodynamics of bimagrumab (BYM338)
Effectiveness and benefits can depend on ingredients and dosing at clinical levels
Impaired cerebral autoregulation and the other metrics of cerebral hemodynamics reported by Koch et al (rapid rise in MCA pulsatility, drop in cerebrovascular resistance index) in the immediate post-exercise period align well with the phenomenon of weightlifters blackout in which individuals may experience syncope or pre-syncope immediately following high intensity resistance exercise, particularly when in the upright standing position due to the sudden pressure drop upon release of the external load (Compton et al., 1973)
Yes, tirzepatide can be associated with hair loss, but the effect is not common, and most evidence points to an indirect cause
"Tirzepatide Versus Semaglutide Once Weekly as Adjunct to a Reduced-Calorie Diet and Increased Physical Activity in Adult Participants With Obesity (SURMOUNT-5)." NCT05822830
