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Patients should discuss the duration of their supplementation with a healthcare provider to balance short-term energy benefits against long-term cardiovascular risks

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The main underlying causes to address when considering treatment include: ACh synthesis Micronutrient deficiencies Methylation issues (needed for choline synthesis) Nervous system function Mitochondrial function Thyroid hormone function HCl, gallbladder and pancreatic function Inflammation Diet Herbs Herbs that improve gut motility can be very helpful to alleviate the symptoms until the root cause can be uncovered and addressed

[3] Sinclair C, Gilchrist J, Hennessey J, et al