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These include deficiencies in protein, vitamin B-12, copper, iron, and of course stress
Curr Opin Cell Biol (1997) 9(2):193204
(2004) reported that in elderly subjects with documented pineal insufficiency, epithalamin administration was associated with measurable changes in circadian melatonin release patterns, including shifts in nocturnal melatonin peak levels toward values observed in younger cohorts (6)
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