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Therefore, the present study investigated potentially BSO-sensitive cancer cell types and a sensitivity marker for GCLC inhibitors using BSO in cultured cancer cells

Recent studies have confirmed this hypothesis, showing that T4 treatment reduces inflammation, enhances antioxidant defenses, and upregulates GPX4 expression in high-fat diet (HFD)-induced NAFLD rats

Yu EW, Gao L, Stastka P, Cheney MC, Mahabamunuge J, Torres Soto M, et al

Direct scavenging of free radicals (especially ROS), inhibition of ROS manufacturing enzymes, and preservation of mitochondrial integrity and function affect redox signaling by activating nuclear factor erythroid-derived 2-like 2 (Nrf2) and peroxisome proliferator-activated receptor alpha (PPAR), and the synthesis of heat shock proteins (HSPs), thioredoxins, sirtuins, and other antioxidant molecules are pathways through which L-carnitine and its derivatives modulate oxidative stress conditions [14, 38]

Effects of canagliflozin on body weight and relationship to HbA1c and blood pressure changes in patients with type 2 diabetes