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These opposing effects on bowel habitsconstipation in some individuals and diarrhoea in othersreflect individual variation in how the gastrointestinal system responds to GLP-1 receptor activation
10.1016/S0161-6420(98)95019-9
The equivalent injectable dose would therefore be approximately 2mg to 2.4mg weekly, since injectable bioavailability approaches 100%
In cases of chronic gastrointestinal conditions, I recommend sublingual tablets or liquid drops to bypass the gut
The GLP-1 Companion review looks at a support supplement designed to work alongside other GLP-1 approaches
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