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Glutathione (GSH) is a tripeptide, gamma-glutamyl-cysteinyl-glycine, which readily undergoes oxidation to form a disulphide-linked hexapeptide, oxidised glutathione, generally abbreviated to GSSG The table below shows the concentrations of GSH and GSSG in red cells from 10 control subjects, and Samuel W, before and after incubation with acetylphenylhydrazine

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FG-4592, a hypoxia-inducible factor-prolyl hydroxylase inhibitor, has been found to elevate intracellular GSH levels and decrease iron accumulation when administered as a pre-treatment (166)

This can help reduce the risk of complications