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This study provides novel design principles and therapeutic strategies for developing electrically active bone repair materials

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Abbreviations ACAD: Acyl-CoA dehydrogenase KG: -Ketoglutarate BGC: Biosynthetic gene cluster CHM: Chalkophomycin gig : Gold-induced genes Hbt: Histidinobutyrine HDO: Heme oxygenase-like dimetal oxidase INLP: Isonitrile lipopeptide INS: Isonitrile synthase MNIO: Multinuclear non-heme iron-dependent oxidase NMR: Nuclear magnetic resonance spectroscopy NRPS: Non-ribosomal peptide synthetase NTHi: Nontypeable Haemophilus influenzae PKS: Polyketide synthase pMMO: Particulate methane monooxygenase RiPP: Ribosomally synthesized, post-translationally modified peptide SAM: S -Adenosylmethionine References Quist DA, Diaz DE, Liu JJ, Karlin KD (2017) J Biol Inorg Chem 22:253288