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The body weight reduction was statistically significantly greater for oral semaglutide versus placebo in healthy subjects (treatment difference in change from baseline, oral semaglutideplacebo: 4.3 kg [95% CI 6.3, 2.3
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Risk factor screening and prediction modeling of gastrointestinal adverse reactions caused by GLP-1RAs
Most importantly, cardiovascular monitoring remains warranted despite favorable population-level profiles, as long-standing severe obesity can itself affect cardiac structure and function, and individual-level events are not precluded
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