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To determine the tissue distribution of RNK06138 in vivo , we examined its pharmacokinetic properties in tumor-bearing (A427-xenografted cell) mice
Research shows it affects over thousands of genes in cells
Ann Otol Rhinol Laryngol
These results support a useful selectivity window for NNMT research, but they were obtained with a limited panel of related enzymes and do not rule out every possible off-target interaction
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