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Kojic acid, on the other hand, is a topical ingredient that works directly on the skins surface to lighten dark spots and improve tone
Someone following a perfect protocol with a contaminated or underdosed product will see zero results
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The mechanism and timeline are the same as for male patients, with some adjustments in the protocol for patients in perimenopause or menopause where hormonal changes affect collagen synthesis and healing rates
Once in the nucleus, Nrf2 binds to antioxidant response elements (AREs) and induces the expression of over 500 cytoprotective genes, including superoxide dismutase (SOD) and glutathione peroxidase (GPx) 9,10,11 , thereby enhancing the cells resilience against more significant stressors
