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What the Evidence Shows (and What It Doesnt) A recent real-world study (n = 94) on semaglutide + cyanocobalamin (compounded) showed average weight loss of ~4.11 kg (4.6%) in 3 months , along with favorable reductions in fat mass and improvements in body composition PubMed However, large controlled trials of this exact combination are lacking

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2019 Update to: management of hyperglycemia in type 2 diabetes, 2018

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It has also been found that, in addition to effectively treating diabetes and obesity, semaglutide, tirzepatide, and similar drugs reduce the risk of heart attacks, strokes, and death from cardiovascular causes by 20%

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