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Gut Hormone Implicated in NMOSD-Related Brain Inflammation The gut hormone glucagon-like peptide 1 (GLP-1) and its receptor (GLP-1R) may contribute to brain inflammation and nerve overactivity in patients with neuromyelitis optica spectrum disorder (NMOSD)
I hit a major milestone in getting the paper done, but only had a week until the next deadline
Entre os estudos em andamento: SURMOUNT-MMO (Tirzepatida): avalia desfechos cardiometablicos em obesos, incluindo incidncia de neoplasias como desfecho secundrio SELECT anlise de subgrupos oncolgicos (semaglutida): anlises exploratrias dos dados do SELECT focadas em incidncia de cncer esto sendo publicadas progressivamente desde 2024 Estudos LEADER e SUSTAIN reanlise: revises retrospectivas focadas em incidncia oncolgica em coortes de pacientes diabticos com longa exposio a GLP-1 Os prximos 35 anos devem trazer evidncias muito mais slidas sobre o papel dos agonistas GLP-1 na preveno oncolgica
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