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This suppression is reversible but can persist for 24 weeks after discontinuation depending on dose and duration
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10.1186/1471-2202-7-29 Summary Keywords amyotrophic lateral sclerosis, energy metabolism, medium chain fatty acids, mitochondria, metabolic treatment Citation Tefera TW and Borges K (2017) Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic Treatments
In the insulin resistant states, fatty acids are favored as an energy source over glucose, which is thus associated with increased fatty acid oxidation, and an overall decrease in glycolysis and glucose oxidation [30]