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In the trial, patients had an eGFR of at least 30 mL/min per 1.73 m2 of body-surface area and were to receive either empagliflozin (at a dose of 10 mg or 25 mg) or placebo once daily

Davies et al., JAMA 2021) reported psychiatric adverse events at similar rates between semaglutide and placebo groups, suggesting no clear direct causation

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