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This transcriptional suppression of inflammatory programs creates a cellular environment favoring repair over continued immune activation, while GHK-Cu's antioxidant propertiesincluding blocking formation of reactive oxygen species, detoxifying lipid peroxidation products such as acrolein, and preventing tissue-damaging free iron releaseprotect regenerating tissues from oxidative damage that can perpetuate inflammatory cycles
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HC B cells (n = 6) were cultured in 20% HC or SLE serum supplemented with LPX-1 for 72 hours, and plasmacytoid dendritic cells (pDC) (n = 3) were cultured for 24 hours, the level of IgG was assessed by ELISA and type I IFNs by flow cytometry individually
