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However, pregnant or breastfeeding women, and those with certain medical conditions, should avoid the treatment unless cleared by a doctor
This is because the coordination state of the copper ions in the GHK-Cu and the tripeptide is crucial to its efficacy, and acidic substances can easily dissociate the copper ions in the complex, which will reduce the activity of superoxide dismutase
This work was supported by the Key Research and Development Program of Shandong Province (Grant No
J Am Med Assoc 1999;282:2305-12
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