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Antibody drug conjugates (ADCs) are an emerging class of antitumor agents that selectively target tumor cells and deliver concentrated cytotoxic payloads through an antibody-mediated process, effectively sparing normal tissue
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Zhangs study demonstrated that the synthesis of GSH is intricately linked to serine metabolism, with its metabolic byproducts lactate and 2-hydroxyglutarate (2-HG) suppressing the cytotoxic function of T cells
Tepes M, Gojkovic S, Krezic I, Zizek H, Vranes H, Madzar Z, et al
