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As the enhanced absorption of oral semaglutide from the stomach is facilitated by SNAC in a pH-dependent manner, the impact of agents that influence gastric pH on the pharmacokinetics of oral semaglutide required investigation
It's an analogue of gastric inhibitory polypeptide (GIP), which is a human hormone that stimulates the release of insulin from the pancreas
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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